Welcome to our lab. We study genomic mechanisms of human disease.

We study transcriptional regulation, one of the uses of the word ‘epigenetics’.

We study DNA sequence variation in the non-coding 98.8% of the human genome, identifying functional non-coding variants (FNCVs).

We study cells in a tissue, the fates that created them, and reprogramming of their functions.

We study how genetic ancestry influences disease risk, and how this intersects with social determinants of health and health care provision.

We study rare diseases, and how the insights above allow us to understand why the rare disease occurred in an individual or family.

Our goal is to improve human health, with a focus on the communities of The Bronx and New York City.